In this study a latest IR spectroscopic procedure was narrated for quantitative determination of amikacin sulphate from solid dosage form. For IR spectroscopic method KBr disc technique, base line method has been used. The specific absorption bands at 3253 cm-1 were chosen as OH stretching mainly for hydroxyl group respectively. In this method Beer’s law was followed in the concentration range 0.8 to 2.0% w/w in KBr disc. The regression equation was found to be y = 0.122 x-0.1233 with correlation coefficient 0.9973 and the assay was found to be 97.9% with RSD of 1.153%.
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